官网链接
折扣/货期| 货号：40841-10 mg | 规格：10 mg | 目录价：￥1474 |
| 货号：40841-25 mg | 规格：25 mg | 目录价：￥3055 |
| 货号：40841-5 mg | 规格：5 mg | 目录价：￥871 |
| 货号：40841-50 mg | 规格：50 mg | 目录价：￥5668 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MMRi62
产品描述:
A degrader of MDM2 and MDM4; induces ubiquitination of MDM2 and MDM4 in NALM6 leukemia cells at 5 µM and selectively decreases the proliferation of MV4-11 leukemia cells (IC50 = ~0.12 µM) over primary human PBMCs(IC50 = ~15 µM); decreases the growth of HL-60 promyeoloblast leukemia cells and multidrug-resistant HL-60/DOX cells (IC50s = 0.34 and 0.22 µM, respectively); induces apoptosis in MV4-11 leukemia cells at 2 µM; decreases the number of CFUs in a panel of ten primary patient-derived leukemia cells expressing either wild-type or mutant p53 (mean IC50s = 11.7 and 12.8 µM, respectively); decreases tumor size in a HL-60/DOX mouse model of drug-resistant leukemia at 100 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
396.26882
产品形式:
A solid
纯度:
≥95%
CAS号:
352693-80-2
分子式:
C21H15Cl2N3O
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