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折扣/货期| 货号：SIH-423-5MG | 规格：5 mg | 目录价：￥1353.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
A83 01
别名:
3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide, A-83-01, A83-01
产品描述:
ALK kinase inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
421.5
产品形式:
White to beige powder
产地:
加拿大
功能与背景:
A83-01 is a selective inhibitor of TGF-β type I receptor ALK5 kinase. It blocks phosphorylation of Smad2 and inhibits TGF-β-induced epithelial-to-mesenchymal transition. A 83-01 also inhibits the transcriptional activity induced by TGFβ type I receptor ALK-5, activin type IB receptor ALK-4 and nodal type I receptor ALK-7.
纯度:
≥98% (HPLC)
来源:
Synthetic
CAS号:
909910-43-6
分子式:
C25H19N5S
溶解度:
Soluble to 50 mM in DMSO
PubChem CID:
16218924
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