| 货号:25983-1 mg | 规格:1 mg | 目录价:¥536 |
| 货号:25983-10 mg | 规格:10 mg | 目录价:¥3296 |
| 货号:25983-25 mg | 规格:25 mg | 目录价:¥6914 |
| 货号:25983-5 mg | 规格:5 mg | 目录价:¥1769 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Acalisib
别名:
GS-9820
产品描述:
An inhibitor of p110δ (IC50 = 12.7 nM); selective for p110δ over the class I PI3Ks subunits p110α, p110β, p110γ, the class II PI3K CIIβ, and the class III PI3K hVPS34 (IC50s = 5.4, 3.3, 1.4, 10, and 12.6 μM, respectively), as well as PIP5Kα, PIP5Kβ, DNA-PK, and mTOR (IC50s = >10 μM); reduces lamellipodia spreading and induces lamellipodia retraction in rat osteoclasts at 1 μM; reduces proliferation of multiple myeloma tumor cells alone and in combination with melphalan in vitro and reduces tumor growth when administered in combination with melphalan in an LAGk-2 mouse xenograft model
保存温度:
-20
运输温度:
-20
预期分子量:
401.396723
产品形式:
A solid
纯度:
≥98%
CAS号:
870281-34-8
分子式:
C21H16FN7O
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