深圳欣博盛生物科技有限公司 a1

SH-4-54
货号:25982-1 mg 规格:1 mg 目录价:¥482.4
货号:25982-10 mg 规格:10 mg 目录价:¥2934.6
货号:25982-25 mg 规格:25 mg 目录价:¥5628
货号:25982-5 mg 规格:5 mg 目录价:¥1608
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SH-4-54
产品描述:
A STAT3 inhibitor (IC50 = 4.7 μM for STAT3 homodimer DNA binding activity); selectively inhibits STAT3 homodimer over STAT1 and STAT5 homodimer and STAT3:STAT1 heterodimer DNA binding in EGF-stimulated NIH3T3/hEGFR nuclear extracts containing activated STAT1, STAT3, and STAT5; decreases STAT3 iNOS, Survivin, and Bcl-2 promoter occupancy in MDA-MB-231 cells; inhibits growth of glioma, breast, and prostate cancer cell lines that express constitutively active STAT3 (IC50s = 1-7.4, 3.8-4.5, and 5.3-5.8 μM, respectively); inhibits tumor growth in the U251MG glioma and MDA-MB-231 breast cancer mouse xenograft models at 3 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
610.593176
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1456632-40-8
分子式:
C29H27F5N2O5S
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