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折扣/货期| 货号：20853-10 mg | 规格：10 mg | 目录价：￥482.4 |
| 货号：20853-100 mg | 规格：100 mg | 目录价：￥3162.4 |
| 货号：20853-25 mg | 规格：25 mg | 目录价：￥1031.8 |
| 货号：20853-50 mg | 规格：50 mg | 目录价：￥1715.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Acitretin
别名:
all-trans Acitretin|Ro 10-1670|Ro 10-1670/000
产品描述:
A retinoid and an active metabolite of the retinoid etretinate that has antiproliferative activities; binds to CRABP-1 and CRABP-II (Kds = 3 and 15 nM, respectively, for the mouse recombinant proteins) but has low affinity for human recombinant retinoic acid receptor-retinoid X receptor (RAR-RXR) heterocomplexes; inhibits proliferation (IC50 = 6.6 µM) and suppresses TNF-α- and IFN-γ-induced protein levels of STAT1, NF-ĸB, and RANTES in HaCaT keratinocytes when used at 50 µM; inhibits proliferation of HL-60, SCC4, SCC15, and A431, but not MCF-7, cancer cells, at 30 µM; decreases the severity of psoriatic-like skin lesions in K14-VEGF transgenic mice (20 µg per mouse)
保存温度:
-20
运输温度:
-20
预期分子量:
326.4
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
55079-83-9
分子式:
C21H26O3
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