深圳欣博盛生物科技有限公司 a1

ADAMTS4 antibody, C-term
货号:GTX81446 规格:400μl 目录价:¥5600
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ADAMTS4 antibody, C-term
别名:
ADAM metallopeptidase with thrombospondin type 1 motif 4 , ADAMTS-2 , ADAMTS-4 , ADMP-1
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
KLH conjugated synthetic peptide between 705-736 amino acids from the C-terminal region of human ADAMTS4.
克隆性:
Polyclonal
克隆号:
纯化方式:
Protein A purified, followed by peptide affinity purification.
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradation of aggrecan. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询