Adenovirus Fiber trimer antibody [2A6]-抗病毒抗体-深圳欣博盛生物科技有限公司

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Adenovirus Fiber trimer antibody [2A6]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX23232

规格：500μl

目录价：￥5000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Adenovirus Fiber trimer antibody [2A6]

别名:

Adenovirus fiber , AD fiber

反应种属:

Adenovirus

宿主来源:

Mouse

实验应用:

ICC/IF, WB

靶标/特异性:

Recognizes only trimers (high molecular weight bands 180 - 200kDa) on Western blots of unboiled Ad2 and Ad5 fiber proteins and shows immunofluorescence with Ad5 fiber mutant H5ts142 infected cells at 32ºC but not at 39.5ºC.

同种型:

IgG2a

免疫原:

UV irradiated Ad2 virus.

克隆性:

Monoclonal

克隆号:

2A6

纯化方式:

Protein A affinity purified

偶联:

Unconjugated

产品浓度:

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

Adenovirus capsid proteins are synthesized in the cytoplasm and transported to the nucleus for assembly into the virus particles. The three major capsid proteins (hexon, penton base, and fiber) are synthesized late in infection. Fiber plays a crucial role in adenovirus infection by attaching the virus to a specific receptor on the cell surface. Ad2 and Ad5 fibers are proposed to consist of three domains: an N-terminal tail that interacts with penton base, a shaft composed of 22 repeats of a 15 amino acid segment that forms beta sheet and beta bends, and a knob at the C terminus that contains the type specific antigen and is responsible for binding to the cell surface receptor. It is shown that the fiber of Ad2 is most likely a trimer when found on the virion.

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