AdipoRon-激动剂-深圳欣博盛生物科技有限公司

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AdipoRon

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CR1-0154-M010	规格：10 mg	目录价：￥600
货号：AG-CR1-0154-M050	规格：50 mg	目录价：￥2400

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

AdipoRon

别名:

2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide

产品描述:

Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low µm concentration [1, 2]. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells [1]. Activates peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) which boosts mitochondrial proliferation and energy metabolism [1]. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms [1]. Rescued the shortened lifespan of db/db mice (AdipoRs KO) on high-fat diet [1]. Reduces expression levels of genes encoding inflammatory cytokines such as TNF-alpha, IL-6 and CCL-2 in WAT of WT mice but not db/db mice [1].

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

428.5

产品形式:

solid

产地:

瑞士

纯度:

>98% (NMR)