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折扣/货期| 货号：SIH-425-25MG | 规格：25 mg | 目录价：￥4867.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AG 1478
别名:
N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine, 4-(3-Chloroanilino)-6,7-dimethoxyquinazoline
产品描述:
EGFR kinase inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
315.8
产品形式:
White to light yellow solid
产地:
加拿大
功能与背景:
AG 1478 is a potent and selective inhibitor of EGFR. It does so by reducing EGF-stimulated DNA synthesis (seen in rat fibroblasts) and blocking EGF-dependent src-family kinase activation and p21/Cip 1/WAF1 induction (seen in A431 cells). AG 1478 is cell-permeable and active in vivo.
纯度:
≥98% (HPLC)
来源:
Synthetic
CAS号:
153436-53-4
分子式:
C16H14ClN3O2
溶解度:
Soluble in DMSO (10 mg/ml)
PubChem CID:
2051
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