| 货号:29487-10 mg | 规格:10 mg | 目录价:¥2452 |
| 货号:29487-25 mg | 规格:25 mg | 目录价:¥5065 |
| 货号:29487-5 mg | 规格:5 mg | 目录价:¥1380 |
| 货号:29487-50 mg | 规格:50 mg | 目录价:¥6727 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
AIM 100
产品描述:
An ACK1/TNK2 inhibitor (IC50 = 21.58 nM); selective for ACK1/TNK2 over Abl1, BTK, LCK, and LYN (IC50s = 705.9, 871.7, 432.3, and 346.7 nM, respectively), as well as a panel of 25 additional kinases; inhibits EGF-induced increases in ATM protein levels, ACK1/TNK2 and androgen receptor phosphorylation, and pTyr267-androgen receptor binding to the ATM enhancer in LAPC4 cells at 1 μM; inhibits the growth of LNCaP and LAPC4 cells in a concentration-dependent manner and induces cell cycle arrest at the G0/G1 phase at 3 μM; enhances radiation-induced tumor growth reduction in an LNCaP-caAck CRPC mouse xenograft model at 4 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
371.43186
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
873305-35-2
分子式:
C23H21N3O2
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