深圳欣博盛生物科技有限公司 a1

SCIO 469
货号:29484-1 mg 规格:1 mg 目录价:¥496
货号:29484-10 mg 规格:10 mg 目录价:¥3296
货号:29484-5 mg 规格:5 mg 目录价:¥1769
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SCIO 469
别名:
Talmapimod
产品描述:
A p38 MAPK inhibitor (IC50 = 9 nM for p38α); 10-fold selective for p38α over p38β MAPK and 2,000-fold selective over a panel of 20 additional kinases; inhibits secretion of IL-6 from multiple myeloma patient-derived BMSCs in a concentration-dependent manner; increases PS-341-induced growth inhibition, DNA fragmentation, and caspase-8 and PARP cleavage in MM.1S cells at 100 and 200 nM; reduces microvessel density and tumor load and increases survival in a 5T33MM murine myeloma model at 150 and 450 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
513.003363
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
309913-83-5
分子式:
C27H30ClFN4O3
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