| 货号:GTX11755 | 规格:100μl | 目录价:¥6400 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
alpha Fodrin antibody [D8B7]
别名:
spectrin alpha, non-erythrocytic 1 , EIEE5 , NEAS , SPTA2
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, ICC/IF, IHC-Fr, WB
靶标/特异性:
Clone D8B7 is developed against the alpha II spectrin SH3 domain (Xu et al., 2001). Clone D8B7 is a specific marker for human, rat and mouse alpha II spectrin or fodrin. In cerebellar cell cultures, it labelsaxons and periphery of cell bodies consistent with localization of fodrin(reviewed in Bennett, 1993; Goodman, 1995 & De Matteis, 2000). It does notcrossreact with alpha I (erythroid) spectrin SH3 domain.
同种型:
IgG2b
免疫原:
Recombinant alpha II spectrin (non-erythroid spectrin or fodrin) SH3 domain (Human).
克隆性:
Monoclonal
克隆号:
D8B7
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Ascites, no preservatives.
生产商:
GeneTex
功能与背景:
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
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