Animal-Free Recombinant Human IL-37 (IL-1F7)-无动物成分蛋白-深圳欣博盛生物科技有限公司

首页产品中心无动物成分蛋白

Animal-Free Recombinant Human IL-37 (IL-1F7)

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：AF-200-39-100UG	规格：100 ug	目录价：￥13743
货号：AF-200-39-1MG	规格：1 mg	目录价：￥58636
货号：AF-200-39-250UG	规格：250 ug	目录价：￥25610
货号：AF-200-39-25UG	规格：25 ug	目录价：￥3443
货号：AF-200-39-500UG	规格：500 ug	目录价：￥38041
货号：AF-200-39-5UG	规格：5 ug	目录价：￥1498

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Animal-Free Recombinant Human IL-37 (IL-1F7)

别名:

Interleukin-37, IL-1F7, IL-1ζ (zeta), IL-1H4

产品描述:

The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-37 (IL-1F7), which acts as a modulator of the immune response. Reduction of IL-37 synthesis in PBMCs leads to increased production of proinflammatory cytokines including IL-1 alpha, IL-1beta, IL-6 and TNF- alpha. The role of IL-37 as an inhibitor of the innate inflammatory response is also corroborated by the observation that it is highly expressed in synovial tissue from patients with rheumatoid arthritis. Full length IL-37 resides primarily in the cytoplasm, but after activation through cleavage by CASP1, it can translocate to the nucleus where it exerts its activity by direct interaction with SMAD3. Recombinant Human IL-37 is a 19.4 kDa protein consisting of 174 amino acids, corresponding to the mature activated form of IL-37.

宿主来源:

E.coli

保存温度:

Minus 20C

运输温度:

Room Temperature

产品形式:

Bulk

产地:

美国

生产商:

PeproTech