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折扣/货期| 货号：3413-0.02 mg | 规格：0.02 mg | 目录价：￥1345.5 |
| 货号：3413-0.1 mg | 规格：0.1 mg | 目录价：￥6084 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Anthrax Protective Antigen Antibody
别名:
Anthrax Protective Antigen Antibody: pag, pXO1-110, BXA0164, GBAA_pXO1_0164, Protective antigen, Anthrax toxins translocating protein, PA
反应种属:
Bacteria
宿主来源:
Rabbit
实验应用:
ELISA
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Anthrax Protective Antigen Antibody is affinity chromatography purified via peptide column.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
Anthrax Protective Antigen antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Anthrax Protective Antigen Antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
Anthrax Protective Antigen Antibody: Anthrax infection is initiated by the inhalation, ingestion, or cutaneous contact with Bacillus anthracis endospores. B. anthracis produces three polypeptides that comprise the anthrax toxin: protective antigen (PA), lethal factor (LF), and edema factor (EF). PA binds to two related proteins on the cell surface; these are termed tumor epithelial marker 8 (TEM8)/anthrax toxin receptor (ATR) and capillary morphogenesis protein 2 (CMG2), although it is still unclear which is physiologically relevant. Following PA binding to its receptor, PA is cleaved into two fragments by a furin-like protease. The bound fragment binds both LF and EF; the resulting complex is then endocytosed which allows the translocation of LF and EF into the cytoplasm. These toxins are usually sufficient to cause rapid cell death, and often the death of the organism.
Accession #:
AAF86457
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