| 货号:JAI-MOG-020P | 规格:20 ug | 目录价:¥4130 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
anti-8-Hydroxy-2'-deoxyguanosine [8-OHdG], mAb (N45.1)
产品描述:
8-hydroxy-2'-deoxyguanosine (8-OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals (incl. singlet oxygen and direct photodynamic action) that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer’s disease. 8-OHdG is popular as a sensitive, stable and integral marker of oxidative damage in cellular DNA and can be detected in tissue, serum, urine and other biomaterials.
宿主来源:
Ascites
实验应用:
ELISA, IHC
靶标/特异性:
Recognizes 8-OHdG. Does not cross-react with 19 analogues of 8-OHdG (guanosine (G), 7-methylG, 6-SHG, 8-bromoG, dA, dC, dT, dI, dU, dG, O6-methyldG, 8-OHdA, guanine (Gua), O6-methylGua, 8-OHGua, uric acid, urea, creatine, creatinine). Minimal cross-reactivity with 8-sulfhydrylG and 8-OHG (less than 1%).
同种型:
Mouse IgG1kappa
免疫原:
8-Hydroxy-2’-deoxyguanosine (8OHdG) conjugated keyhole limpet hemocyanin.
克隆号:
N45.1
保存温度:
+4°C
运输温度:
BI
产品形式:
solid
存储溶液:
Lyophilized. Contains 10mM PBS, pH7.4 containing 1.0% BSA.
产地:
瑞士
上一个:anti-Nitrotryptophan (NW), mAb (117C)
下一个:anti-8-Hydroxy-2'-deoxyguanosine [8-OHdG], mAb (N45.1)
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