anti-ACE2 (human), pAb-多抗-深圳欣博盛生物科技有限公司

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anti-ACE2 (human), pAb

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-25A-0042-C100

规格：100 ug

目录价：￥1920

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-ACE2 (human), pAb

别名:

SARS Receptor; Angiotensin-converting Enzyme 2; ACEH; Metalloprotease MPROT15; SARS-CoV-2 Receptor

产品描述:

Angiotensin-converting enzyme2 (ACE2) is an ectoenzyme (carboxypeptidase) with an extracellular catalytic domain that predominantly localizes at the plasma membrane and is thereby able to hydrolyze circulating peptides. ACE2 has approximately 42% sequence identity with ACE, and its cytoplasmic and transmembrane domains show 48% homology to the protein collectrin that plays a critical role in the amino acid absorption of the kidney. ACE2 converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. ACE2 is involved in the regulation of systemic blood pressure and has direct effects on cardiac functions. It is expressed predominantly in endothelial cells of the lung, gut, heart and kidney. ACE2 together with the protease TMPRSS2 acts as a functional receptor for SARS coronavirus as well as for the new highly pathogenic coronavirus, 2019-nCoV/SARS-CoV-2, which is cause for pneumonia COVID-19.

宿主来源:

Rabbit

实验应用:

ELISA, WB

靶标/特异性:

Recognizes human ACE2. Detects a band of ~90kDa by Western blot.

免疫原:

Recombinant human ACE2.

产品浓度:

1mg/ml

保存温度:

+4°C