| 货号:REV-31-1336-00-C025 | 规格:25 ug | 目录价:¥3122 |
| 货号:REV-31-1336-00-C100 | 规格:100 ug | 目录价:¥6972 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
anti-Acetyl-Histone H2A.X (Lys5), Rabbit Monoclonal (RM445)
别名:
H2A.X K5ac
产品描述:
Histones are proteins that package DNA into nucleosomes. Histones are responsible for maintaining the shape and structure of a nucleosome. One chromatin molecule is composed of at least one of each core histones per 100 base pairs of DNA. There are five families of histones known to date; these histones are termed H1/H5, H2A, H2B, H3, and H4. H2A is considered a core histone, along with H2B, H3 and H4. Core formation first occurs through the interaction of two H2A molecules. Then, H2A forms a dimer with H2B; the core molecule is complete when H3-H4 also attaches to form a tetramer. Histone H2A is composed of non-allelic variants, including H2A.1, H2A.2, H2A.X, and H2A.Z. H2A packages DNA molecules into chromatin and has been correlated with DNA modification and epigenetics. H2A plays a major role in determining the overall structure of chromatin and regulates gene expression. Protein modification on histone H2A exist and can sometimes result in a change in function. Different H2A variants were exploited to have different functions, genetic sequences and modifications.
宿主来源:
Rabbit
实验应用:
WB, Multiplex
靶标/特异性:
This antibody reacts to Histone H2A.X acetylated at Lysine 5 (K5ac). It shows no cross-reactivity with non-modified Lysine 5 or other acetylated Lysines in histone H2A.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to acetyl-Histone H2A.X (Lys5).
克隆号:
RM445
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-Detyrosinated alpha-Tubulin (human), Rabbit Monoclonal (RM444)
下一个:anti-Acetyl-Histone H2A.X (Lys9), Rabbit Monoclonal (RM446)
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