anti-Detyrosinated alpha-Tubulin (human), Rabbit Monoclonal (RM444)-单抗-深圳欣博盛生物科技有限公司

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anti-Detyrosinated alpha-Tubulin (human), Rabbit Monoclonal (RM444)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1335-00-R100

规格：100 ul

目录价：￥5726

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-Detyrosinated alpha-Tubulin (human), Rabbit Monoclonal (RM444)

产品描述:

Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule diversity: the expression of different alpha- and beta-tubulin genes, referred to as tubulin isotypes, and the generation of posttranslational modifications (PTMs) on alpha- and beta-tubulin. Tubulin PTMs include the well-known acetylation or phosphorylation, and others that have so far mostly been found on tubulin, detyrosination/tyrosination, polyglutamylation and polyglycylation. These PTMs might have evolved to specifically regulate tubulin and microtubule functions. Detyrosination is a form of posttranslational modification that occurs on alpha-tubulin. It consists of the removal of the C-terminal tyrosine to expose a glutamate at the newly formed C-terminus. Tubulin polymers, called microtubules, that contain detyrosinated alpha-tubulin are usually referred to as Glu-microtubules while unmodified polymers are called Tyr-microtubules.

宿主来源:

Rabbit

实验应用:

ICC, WB, IF

靶标/特异性:

This antibody reacts to detyrosinated human alpha-Tubulin. It has no cross reactivity to non-detyrosinated alpha-Tubulin.

同种型:

Rabbit IgG

免疫原:

A peptide corresponding to human dTyr alpha-tubulin.

克隆号:

RM444