anti-Alpha Cardiac Actin, Rabbit Monoclonal (RM257)-单抗-深圳欣博盛生物科技有限公司

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anti-Alpha Cardiac Actin, Rabbit Monoclonal (RM257)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1138-00-R100

规格：100 ul

目录价：￥5726

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-Alpha Cardiac Actin, Rabbit Monoclonal (RM257)

别名:

ACTC1

产品描述:

Actins are a family of globular multi-functional proteins that form microfilaments and are important for cell movement and the tensing (contraction) of muscles. ACTC1 (Cardiac alpha actin) together with regulatory proteins tropomyosin and 3 troponins (C, I, and T) forms the thin contractile filament, in turn connecting the myocellular Z-disc with the thick filament protein myosin. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). Mutations in ACTC1 are associated in autosomal dominant heart failure and familial atrial septal defect (ASD). Cardiac (ACTC1) and skeletal (ACTA1) alpha actins differ by only four amino acids (Asp4Glu, Glu5Asp, Leu301Met, Ser360Thr; cardiac/skeletal).

宿主来源:

Rabbit

实验应用:

IHC, WB

靶标/特异性:

The antibody reacts to human and mouse alpha cardiac actin (Actin, alpha cardiac muscle 1). This antibody may also react to bovine or rat alpha-cardiac actin, as predicted by immunogen homology.

同种型:

Rabbit IgG

免疫原:

A synthetic peptide corresponding to the N-terminus of human alpha-cardiac actin.

克隆号:

RM257

产品浓度:

N/A

保存温度:

+4°C

运输温度:

产品形式: