anti-Angiopoietin-2 (human), mAb (rec.) (blocking) (Angy-1-4) (preservative free)
官网链接
折扣/货期| 货号：AG-27B-0015PF-C100 | 规格：100 ug | 目录价：￥4320 |
| 货号：AG-27B-0015PF-C500 | 规格：500 ug | 目录价：￥11760 |
| 货号：AG-27B-0015PF-M001 | 规格：1 mg | 目录价：￥19200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Angiopoietin-2 (human), mAb (rec.) (blocking) (Angy-1-4) (preservative free)
别名:
Ang-2; Ang2; Angpt2; Agpt2
产品描述:
Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context. anti-Angiopoietin-2 (human), mAb (rec.) (blocking) (Angy-1-4) (preservative free) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
宿主来源:
Produced without the use of animals. Purified from CHO cell culture supernatant.
实验应用:
ELISA, FUNC (Blocking)
靶标/特异性:
Recognizes human angiopoietin-2. Does not recognize mouse angiopoietin-2 and human angiopoietin-1.
同种型:
Human IgG2lambda.
免疫原:
Recombinant human angiopoietin-2.
克隆号:
Angy-1-4
偶联:
Preservative Free
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol
产地:
瑞士
纯度:
>95% (SDS-PAGE)
上一个:anti-IL-33 (mouse), mAb (rec.) (blocking) (Bondy-1-1) (preservative free)
下一个:anti-Angiopoietin-2, mAb (rec.) (blocking) (Angy-2-1) (preservative free)
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