anti-IL-33 (mouse), mAb (rec.) (blocking) (Bondy-1-1) (preservative free)
官网链接
折扣/货期| 货号：AG-27B-0013PF-C100 | 规格：100 ug | 目录价：￥4680 |
| 货号：AG-27B-0013PF-C500 | 规格：500 ug | 目录价：￥13200 |
| 货号：AG-27B-0013PF-M001 | 规格：1 mg | 目录价：￥21600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-IL-33 (mouse), mAb (rec.) (blocking) (Bondy-1-1) (preservative free)
别名:
Interleukin-33; IL-1F11; NF-HEV
产品描述:
Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL-33 binds to and signals through ST2 (IL-1R1) and its stimulation recruits MYD88, IRAK, IRAK4 and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38 (MAPK14) and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases and sepsis. Anti-IL-33, mAb (recombinant) (blocking) (Bondy-1-1) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
宿主来源:
Produced without the use of animals. Purified from HEK 293 cell culture supernatant.
实验应用:
ELISA, FUNC (Blocking)
靶标/特异性:
Recognizes mouse IL-33.
同种型:
Mouse IgG2b
免疫原:
Mouse recombinant IL-33.
克隆号:
Bondy-1-1
产品浓度:
Please Inquire.
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
上一个:anti-Myosin IIA (non-muscle) (heavy chain), mAb (rec.) (SF9) (ATTO 488)
下一个:anti-Angiopoietin-2 (human), mAb (rec.) (blocking) (Angy-1-4) (preservative free)
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