anti-ANGPTL4 (human), mAb (Kairos-1)-单抗-深圳欣博盛生物科技有限公司

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anti-ANGPTL4 (human), mAb (Kairos-1)

品牌：Adipogen

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说明书

折扣/货期

货号：AG-20A-0038-C050	规格：50 ug	目录价：￥2640
货号：AG-20A-0038-C100	规格：100 ug	目录价：￥3840

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-ANGPTL4 (human), mAb (Kairos-1)

别名:

Angiopoietin-like Protein 4; FIAF; Fasting-induced Adipose Factor; HFARP; Hepatic Fibrinogen/Angiopoietin-related Protein

产品描述:

ANGPTL4 mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorgenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 is a protein consisting of an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain (FLD). Both domains have distinct biological functions. The coiled-coil domain is responsible for the inhibitory effects on lipoprotein lipase (LPL) converting the active form of LPL into an inactive form, and the FLD domain mediates its antiangiogenic functions. The coiled coil and the FLD domains are separated by a short linker that can be cleaved after secretion. ANGPTL4 appears on the cell surface as the full-length form, where it can be released by heparin treatment. ANGPTL4 protein is then proteolytically cleaved by proprotein convertases (PCs), including furin, PC5/6, paired basic amino acid-cleaving enzyme 4, and PC7.

实验应用:

ELISA, IHC, WB

靶标/特异性:

Recognizes the fibrinogen-like domain (FLD) of human ANGPTL4. Detects a band of ~62kDa and ~35kDa by Western blot. Does not cross-react with other ANGPTL family proteins.

同种型:

Mouse IgG1kappa

免疫原:

Recombinant human ANGPTL4.

克隆号:

Kairos-1

产品浓度:

1mg/ml

保存温度:

+4°C

运输温度:

产品形式: