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折扣/货期| 货号：AG-25B-0033-C100 | 规格：100 ug | 目录价：￥1800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-ANGPTL8 [Betatrophin] (human), pAb (IN108)
别名:
Angiopoietin-like Protein 8; ANGPTL8; Lipasin; Refeeding-induced Fat and Liver Protein; RIFL; Betatrophin
产品描述:
ANGPTL8 (Angiopoietin-like protein 8; RIFL; Lipasin; Betatrophin) is a newly discovered secreted protein of 198 aa that was proposed to promote beta cell proliferation and improve glucose tolerance in mice. ANGPTL8 may also function in inhibition of lipase activity and on serum triglyceride regulation. ANGPTL8 is expressed in the liver and in white and brown adipose tissue of mice. In humans, ANGPTL8 is found to be predominantly expressed in the liver. ANGPTL8 levels are reduced by fasting and are elevated upon insulin resistance and during pregnancy. ANGPTL8, according to preliminary data could bind to the macrophage receptor Marco and also to RTN4R, a neuronal receptor. Recently, a study using ANGPTL8 KO mice showed that ANGPTL8 does not play a role in beta cell proliferation nor in glycemic control as previously thought, but regulates plasma triglyceride levels.
宿主来源:
Rabbit
实验应用:
ELISA, WB
靶标/特异性:
Recognizes human betatrophin.
免疫原:
Recombinant human ANGPTL8 (betatrophin).
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
产地:
瑞士
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