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折扣/货期| 货号：REV-31-1311-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Annexin A1 (human), Rabbit Monoclonal (RM424)
别名:
Lipocortin-1; p35; Annexin-1; Calpactin-2; Calpactin II; Lipocortin I; Chromobindin-9; Phospholipase A2 Inhibitory Protein
产品描述:
The annexin superfamily consists of 13 calcium or calcium and phospholipid binding proteins with high biological and structural homology. Annexin-1 (ANXA1) is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Loss of function or expression of this gene has been detected in multiple tumors. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity, can accumulate on internalized vesicles after EGF-stimulated endocytosis and may be required for a late stage in inward vesiculation. Annexin A1 has also been identified as one of the 'eat-me' signals on apoptotic cells that are to be recognized and ingested by phagocytes. Annexin A1, as an endogenous anti-inflammatory mediator, has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis and tumorigenesis and cancer development.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
RM424 reacts to human Annexin A1.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to the N-terminus of human Annexin A1.
克隆号:
RM424
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
促销活动
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