| 货号:REV-31-1310-00-R100 | 规格:100 ul | 目录价:¥5726 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
anti-TRK (pan) (human), Rabbit Monoclonal (RM423)
别名:
Tropomyosin Receptor Kinase; Tyrosine Receptor Kinase; High Affinity Nerve Growth Factor Receptor
产品描述:
The family of neurotrophic tyrosine kinase (NTRK1/2/3) gene encodes TrkA, TrkB and TrkC protein kinases. The three family members are activated by different neurotrophins: TrkA is activated by Nerve growth factor (NGF), TrkB by Brain-derived neurotrophic factor (BDNF) or neurotrophin-4 (NT-4) and TrkC by NT-3. Neurotrophin signaling activates cellular pathways involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, cell growth, differentiation and survival of sympathetic and nervous neurons. TRK, was initially identified in a colon carcinoma, is frequently activated in thyroid papillary carcinomas. Pan-Trk IHC is a time-efficient and tissue-efficient screen for NTRK fusions, particularly in driver-negative advanced malignancies and potential cases of secretory carcinoma and congenital fibrosarcoma.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
RM423 reacts to human TRK. This antibody may also react to mouse or rat TRK, as predicted by immunogen homology.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to the C-terminus of human TRK.
克隆号:
RM423
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
促销活动
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