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折扣/货期| 货号：AG-20T-0132-C100 | 规格：100 ug | 目录价：￥3600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Apaf-1 (human), mAb (2E12)
别名:
Apoptosis Protease-activating Factor 1
产品描述:
Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short helical domains and then several copies of the WD40 repeat domain. Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome, mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis.
实验应用:
ELISA, ICC, IHC, IP, WB
靶标/特异性:
Recognizes the CARD domain of human Apaf-1. Does not cross-react with mouse or rat Apaf-1.
同种型:
Rat IgG2akappa
免疫原:
Recombinant human Apaf-1 (aa 1-464) containing the N-terminal CARD and CED-4 homologous domains.
克隆号:
2000000000000
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 0.02% sodium azide.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.1EU/µg purified protein (LAL test; Lonza).
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