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折扣/货期| 货号：AG-20T-0131-C100 | 规格：100 ug | 目录价：￥3840 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Bmf (mouse/rat), mAb (17A9)
别名:
Bcl-2-modifying Factor
产品描述:
Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.
实验应用:
ELISA, FACS, ICC, IHC, IP, WB
靶标/特异性:
Recognizes an epitope within the peptide sequence aa 13-27 of mouse and rat Bmf. Detects bands of ~25kDa and ~30kDa by Western blot, corresponding to endogenous Bmf and BmfL. Does not cross-react with human Bmf.
同种型:
Rat IgG2akappa
免疫原:
Recombinant full length mouse Bmf and synthetic peptides corresponding to aa 13-27 and aa 112-126 of mouse Bmf.
克隆号:
17A9
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 0.02% sodium azide.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.1EU/µg purified protein (LAL test; Lonza).
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