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折扣/货期| 货号：AG-20T-0143-C100 | 规格：100 ug | 目录价：￥3840 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-BimS/EL/L, mAb (10B12)
别名:
BCL2L11; Bcl-2-like Protein 11; Bcl2-interacting Mediator of Cell Death
产品描述:
Bim belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the Bcl-2 protein family (BCL2, BCL2L1/BCL-X(L) and MCL1) and to act as an apoptotic activator, inducing apoptosis and anoikis. Several variants have been identified. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent.
实验应用:
ELISA, FACS, ICC, IHC, IP, WB
靶标/特异性:
Recognizes an epitope within aa 20-40 of human, mouse, rat, monkey and dog BimL (~19kDa), BimEL (~23kDa), and BimS (~16kDa). Also recognizes the six novel isoforms of human Bim, generated by alternative splicing and lacking the C-terminal hydrophobic region.
同种型:
Rat IgG2akappa
免疫原:
Synthetic peptide corresponding to aa 20-40 of mouse BimL.
克隆号:
10B12
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 0.02% sodium azide and 25% glycerol.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.1EU/µg purified protein (LAL test; Lonza).
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