| 货号:REV-31-1378-00-R100 | 规格:100 ul | 目录价:¥5726 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
anti-CAIX (CA9), Rabbit Monoclonal (RM486)
别名:
Carbonic Anhydrase IX; CA9, Renal Cell Carcinoma-associated Antigen G250; RCC-associated Antigen G250; P54/58N
产品描述:
Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that are inducible by hypoxia, via HIF-1 alpha. CAIX is one of the most inducible genes because of its stability and location within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CAIX results in increased cell death under hypoxia. Therefore, CAIX has become a reliable histochemical marker of hypoxia.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
This antibody reacts to human CAIX (CA9) (Carbonic Anhydrase 9).
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to the C-terminus of human CAIX (CA9) (Carbonic Anhydrase 9).
克隆号:
RM486
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-DDIT3 (human), Rabbit Monoclonal (RM485)
下一个:anti-Phospho-Smad1 (Ser463/465) / Smad5 (Ser463/465) / Smad9 (Ser465/467), Rabbit Monoclonal (RM487)
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