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折扣/货期| 货号：REV-31-1377-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-DDIT3 (human), Rabbit Monoclonal (RM485)
别名:
DNA Damage-inducible Transcript 3 Protein; C/EBP-homologous Protein 10; CHOP-10; GADD153
产品描述:
DDIT3 [GADD153] is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP DDIT3 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of DDIT3 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane. DDIT3 is a multifunctional transcription factor in endoplasmic reticulum (ER) stress response that plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress.
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
This antibody reacts to human DDIT3 (DNA damage-inducible transcript 3 protein).
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to the N-terminus of human DDIT3 (DNA damage-inducible transcript 3 protein).
克隆号:
RM485
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
促销活动
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