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折扣/货期| 货号：REV-31-1143-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Calponin-1, Rabbit Monoclonal (RM262)
别名:
Calponin H1, Smooth Muscle
产品描述:
Calponin-1 is a 34 kDa thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It interacts with actin, tropomyosin and calmodulin. Calponin-1 binds actin to promote and sustain polymerization. The binding of calponin to F-actin inhibits the MgATPase activity of smooth muscle myosin. The expression of Calponion-1 is specific to differentiated mature smooth muscle cells, suggesting a role in contractile functions. It is up-regulated in smooth muscle tissues during postnatal development with a higher content in phasic smooth muscle of the digestive tract. Calponin-1 has been found to be useful in differentiating benign sclerosing lesions of the breast from carcinoma. Calponin-1 positivity has also been noted in malignant myoepithelioma and pleomorphic adenoma of salivary gland origin, as well as angiomatoid malignant fibrous histiocytoma.
宿主来源:
Rabbit
实验应用:
ICC, WB
靶标/特异性:
This antibody reacts to human or mouse Calponin-1.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to the C-terminus of human Calponin-1.
克隆号:
RM262
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-Phospho-Stat3 (Tyr705) (human), Rabbit Monoclonal (RM261)
下一个:anti-p16INK4a (human), Rabbit Monoclonal (RM267)
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