anti-CD40L (human), mAb (rec.) (blocking) (hu5c8) (preservative free)-单抗-深圳欣博盛生物科技有限公司

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anti-CD40L (human), mAb (rec.) (blocking) (hu5c8) (preservative free)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-27B-6002PF-C100

规格：100 ug

目录价：￥4800

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-CD40L (human), mAb (rec.) (blocking) (hu5c8) (preservative free)

别名:

CD40 Ligand; CD154; Tumor Necrosis Factor Ligand Superfamily Member 5;TNFSF5; Gp39; TRAP

产品描述:

CD40 Ligand (CD40L), renamed TNFSF5 but now also known as CD154, TRAP and gp39, is a 34-39kDa type II transmembrane glycoprotein, that belongs to the TNF superfamily, and a surface receptor expressed on activated T cells which acts as a costimulatory molecule to trigger immune responses. CD40L binds to CD40, which is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development and germinal center formation. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells. CD40L levels are increased in serum and in inflamed tissues of patients with autoimmune diseases.

实验应用:

FACS, FUNC, FUNC (Blocking), WB

靶标/特异性:

Recognizes and binds human CD40L with an IC50 of 0.845µg/ml. Cross-reacts with canine CD40L.

同种型:

Human IgG1kappa

免疫原:

Recombinant human CD40L.

克隆号:

hu5c8

偶联:

Preservative Free