anti-Fas (human), mAb (APO-1-1) (preservative free)-单抗-深圳欣博盛生物科技有限公司

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anti-Fas (human), mAb (APO-1-1) (preservative free)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20B-0079PF-C100	规格：100 ug	目录价：￥2160
货号：AG-20B-0079PF-C500	规格：500 ug	目录价：￥7560

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-Fas (human), mAb (APO-1-1) (preservative free)

别名:

CD95; APO-1; TNFRSF6; Tumor Necrosis Factor Receptor Superfamily Member 6; Apoptosis-mediating Surface Antigen FAS

产品描述:

Fas (CD95) is a member of the death receptor (DR) family, a subfamily of the tumor necrosis factor receptor superfamily. The formation of the Fas death-inducing signaling complex (DISC) is the initial step of Fas signaling. Activation of procaspase-8 at the DISC leads to the induction of DR-mediated apoptosis. Stimulation of Fas has also been reported to trigger non-apoptotic pathways. It has been shown that membrane-bound FasL is essential for the cytotoxic activity, whereas soluble FasL appears to promote autoimmunity and tumorigenesis via induction of non-apoptotic pathways, in particular NF-kappaB.

宿主来源:

Purified from concentrated hybridoma tissue culture supernatant.

实验应用:

FACS, FUNC, IHC

靶标/特异性:

Recognizes human Fas.

同种型:

Mouse IgG1

免疫原:

Recombinant human Fas.

克隆号:

APO-1-1