anti-FliD (Pseudomonas aeruginosa), mAb (rec.) (SH1579-B7)-单抗-深圳欣博盛生物科技有限公司

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anti-FliD (Pseudomonas aeruginosa), mAb (rec.) (SH1579-B7)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-27B-6322-C050

规格：50 ug

目录价：￥3492

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-FliD (Pseudomonas aeruginosa), mAb (rec.) (SH1579-B7)

别名:

Flagellar Hook-associated Protein 2; HAP2; Filament Cap Protein

产品描述:

Pathogenic bacteria cause a multitude of deadly human diseases. Pseudomonas aeruginosa is a predominant organism within the hospital environment, an increasingly multidrug-resistant microbe, and the most common gram-negative pathogen causing nosocomial pneumonia in the United States. Nearly all P. aeruginosa infections are associated with compromised host defenses, which may include patients with severe burns, diabetes, cancer, organ transplants or additional immunodeficiencies. Many of these pathogenic bacteria possess flagella, molecular machines responsible for cell motility, adherence to host cells, and pathogenicity. Flagella are helix-shaped hollow attachments formed predominantly by thousands of copies of the protein flagellin (also called FliC), anchored in the bacterial membrane by a hook (or joint) that is attached to the basal body and that is composed of rotary motor proteins. A FliD (also called HAP2) oligomer forms the cap protein complex that is located at the tip of the flagellar filament. This complex controls the distal growth of the filament by regulating the assembly of FliC molecules, which are transported through the hollow filament from the cytoplasm to the tip of the flagellum. In the absence of FliD, flagella are not formed, resulting in impaired motility and infectivity.

宿主来源:

Protein A purified from HEK293 cell culture supernatant.

实验应用:

ELISA, WB

靶标/特异性:

Recognizes FliD from Pseudomonas aeruginosa.

同种型:

Human IgG1

免疫原:

Recombinant FliD (Pseudomonas aeruginosa PAO1 strain, aa 78–273).

克隆号:

SH1579-B7