anti-GFAP, Rabbit Monoclonal (RM246)-单抗-深圳欣博盛生物科技有限公司

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anti-GFAP, Rabbit Monoclonal (RM246)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1127-00-R100

规格：100 ul

目录价：￥5726

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-GFAP, Rabbit Monoclonal (RM246)

别名:

Glial Fibrillary Acidic Protein

产品描述:

GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is expressed in the central nervous system in astrocyte cells. It is involved in many important CNS processes, including cell communication and the functioning of the blood brain barrier. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. GFAP is closely related to the other three non-epithelial type III IF family members, vimentin, desmin and peripherin, which are all involved in the structure and function of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength as well as the shape of cells. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP.

宿主来源:

Rabbit

实验应用:

IHC, WB

靶标/特异性:

This antibody reacts to human and mouse GFAP (Glial fibrillary acidic protein).

同种型:

Rabbit IgG

免疫原:

A peptide corresponding to the N-terminus of human GFAP.

克隆号:

RM246