| 货号:AG-25A-0023-C100 | 规格:100 ug | 目录价:¥3000 |
| 货号:AG-25A-0023-TRIAL | 规格:25 ug | 目录价:¥1620 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
anti-GITRL (human), pAb (25 ug)
别名:
Glucocorticoid-induced TNF Receptor Ligand; AITRL; Activation-inducible TNF-related Ligand; TNFSF18
产品描述:
GITRL is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis, ..). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T-cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.
宿主来源:
Rabbit
实验应用:
ELISA, IHC, WB
靶标/特异性:
Recognizes human GITRL. Detects a band of ~15-17kDa by Western blot. Does not cross-react with mouse GITRL.
免疫原:
Recombinant human GITRL.
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
产地:
瑞士
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