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折扣/货期| 货号：AG-25B-0028-C100 | 规格：100 ug | 目录价：￥4200 |
| 货号：AG-25B-0028-TRIAL | 规格：25 ug | 目录价：￥1620 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-GPx8 (human), pAb (IN103) (25 ug)
别名:
Probable Glutathione Peroxidase 8; GSHPx-8
产品描述:
GPxs are glutathione peroxidases involved in balancing the H2O2 homeostasis in signaling cascades. GPxs have been known to catalyze the reduction of H2O2 or organic hydroperoxides to water or the corresponding alcohols, respectively, typically using glutathione (GSH) as reductant. GPx8 (probable glutathione peroxidase 8) is a 209-aa, 24kDa protein with an N-terminal cytosolic tip, a predicted transmembrane segment and a catalytic domain located in the endoplasmic reticulum (ER) lumen. GPx8 is a CysGPxs with low glutathione peroxidase activity. A recent study identified GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease. GPx8 cleavage by NS3-4A occurs at Cys11, removing the cytosolic tip of GPx8 and was observed in different experimental systems as well as in liver biopsies from patients with chronic hepatitis C.
宿主来源:
Rabbit
实验应用:
ICC, WB
靶标/特异性:
Recognizes human GPx8.
免疫原:
Recombinant GPx8 (human) (aa 38-209) fused to a GST-tag.
产品浓度:
1 mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
产地:
瑞士
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