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折扣/货期| 货号：REV-31-1121-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-HIF-1 alpha (human), Rabbit Monoclonal (RM242)
别名:
Hypoxia-inducible Factor 1-alpha; HIF1A; ARNT-interacting Protein; Basic-helix-loop-helix-PAS Protein MOP1;
产品描述:
HIF1-alpha (HIF1A) is a subunit of HIF1, which is a transcription factor found in mammalian cells cultured under reduced oxygen tension. HIF-1 is a heterodimer consisting of an alpha and beta subunit, both belonging to the basic-helix-loop-helix Per-aryl hydrocarbon receptor nuclear translocator-Sim (PAS) family of transcription factors. HIF1 functions as a transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, HIF-1 activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF1-alpha regulates hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
This antibody reacts to human HIF-1-alpha (Hypoxia-inducible factor 1-alpha).
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to Hypoxia-inducible factor 1-alpha.
克隆号:
RM242
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-Histone H3.3 G34R Mutant (human), Rabbit Monoclonal (RM240) (Biotin)
下一个:anti-Cyclin D1 (human), Rabbit Monoclonal (RM241)
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