| 货号:REV-31-1122-00-R100 | 规格:100 ul | 目录价:¥5726 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
anti-Cyclin D1 (human), Rabbit Monoclonal (RM241)
别名:
CCND1; G1/S-specific Cyclin-D1
产品描述:
Cyclin D1 (PRAD-1, bcl-1) is one of the key cell cycle regulators, and functions in association with cdk4 and/or cdk6 by phosphorylating the Rb protein. Cyclin D1 is a putative proto-oncogene overexpressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL). In addition, cyclin D1 positively regulates protein phosphorylation, mammary gland epithelial cell proliferation, and fat cell differentiation. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. Cyclin D1 has been successfully employed and is a promising tool for further studies in both cell cycle biology and cancer associated abnormalities.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
This antibody reacts to human Cyclin D1. This antibody may also react to bovine, mouse or rat Cyclin D1, as predicted by immunogen homology.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to Cyclin D1.
克隆号:
RM241
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-HIF-1 alpha (human), Rabbit Monoclonal (RM242)
下一个:anti-E-Cadherin (human), Rabbit Monoclonal (RM244)
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