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折扣/货期| 货号：REV-31-1320-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-HSP70 (human), Rabbit Monoclonal (RM432)
产品描述:
HSP70 is a molecular chaperone expressed constitutively under normal conditions to maintain protein homeostasis and is induced upon environmental stress. It functions by acting as molecular chaperones, facilitating protein refolding and preventing protein aggregation. It has been reported that extracellular HSP70 also exhibits immunomodulatory effects on innate and acquired immunity. HSP70 is membrane associated in lysosomes, mitochondria,and the outer surface of cancer cells. It plays a role in vesicle formation and protein trafficking. HSP70 expression in colorectal carcinoma and breast carcinoma has been significantly correlated with low differentiation and poor prognosis, whereas in renal cell carcinoma it has been reported to be associated with good prognosis. Expression of HSPs on the surface of tumor cells, instead of their normal intracellular location, suggests they play a role in inducing an immune response against cancer.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
RM431 reacts to human HSP70.
同种型:
Rabbit IgG
免疫原:
A recombinant human HSP70 protein.
克隆号:
RM432
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
促销活动
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