| 货号:AG-25B-0026-C100 | 规格:100 ug | 目录价:¥1800 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
anti-IGFLR1 (human), pAb (IN101)
别名:
IGF-like Family Receptor 1; Transmembrane Protein 149; TMEM149; U2 Small Nuclear RNA Auxiliary Factor 1-like 4
产品描述:
Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. Mouse IGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNFR family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
宿主来源:
Rabbit
实验应用:
FACS, WB
靶标/特异性:
Recognizes human IGFLR1. Does not recognize mouse IGFLR1.
免疫原:
Recombinant human IGFLR1 (aa 23-154).
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
产地:
瑞士
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