anti-IL-33 (human), pAb-多抗-深圳欣博盛生物科技有限公司

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anti-IL-33 (human), pAb

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-25A-0045-C100

规格：100 ug

目录价：￥1920

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-IL-33 (human), pAb

别名:

Interleukin-33; IL-1F11; NF-HEV

产品描述:

Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.

宿主来源:

Rabbit

实验应用:

ELISA, IHC, WB

靶标/特异性:

Recognizes human IL-33. Detects a band of ~18kDa by Western blot.

免疫原:

Recombinant human IL-33.

产品浓度:

1mg/ml

保存温度:

+4°C