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折扣/货期| 货号：AG-20B-0070-C100 | 规格：100 ug | 目录价：￥4800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-IL-38, mAb (Nhat-1)
别名:
Interleukin-38; Interleukin-1 Family Member 10; IL-1F10
产品描述:
IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 as a IL-1 family receptor antagonist. Il-38 inhibits IL-36 signaling by binding to IL-1R6. IL-38 (aa 20-152) is released from apoptotic cells to limit inflammatory macrophage and downstream Th17 activation by blocking IL1RAPL1 (Interleukin-1 receptor accessory protein-like 1, TIGIRR-2) signaling. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.
宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
实验应用:
ELISA, WB
靶标/特异性:
Recognizes human and mouse IL-38.
同种型:
Mouse IgG2bkappa.
免疫原:
Recombinant human IL-38.
克隆号:
Nhat-1
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
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