anti-LC3B (human), Rabbit Monoclonal (RM293)-单抗-深圳欣博盛生物科技有限公司

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anti-LC3B (human), Rabbit Monoclonal (RM293)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1177-00-R100

规格：100 ul

目录价：￥5726

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-LC3B (human), Rabbit Monoclonal (RM293)

别名:

Autophagy-related Protein LC3 B; Microtubule-associated Proteins 1A/1B Light Chain 3B; MAP1A/MAP1B LC3 B

产品描述:

LC3 is a central protein in the autophagy pathway where it functions in autophagy substrate selection and autophagosome biogenesis. It is the most widely used marker of autophagosomes. Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translational modifications during autophagy. LC3B (Autophagy Marker Light Chain 3B; MAP1A/MAP1B LC3 B) is associated with microtubule assembly and important in neurogenesis. LC3B plays a vital role in autophagy, a process that involves the bulk degradation of cytoplasmic component. Three human LC3 isoforms undergo post-translational modifications during autophagy. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). LC3B is a microtubule-associated protein that mediate the physical interactions between microtubules and components of the cytoskeleton. LC3B may play a role in processes involving cancer, aging, metabolic and neurodegenerative disorders and cardiovascular/pulmonary diseases.

宿主来源:

Rabbit

实验应用:

ICC, IHC, WB

靶标/特异性:

This antibody reacts to human LC3B (Autophagy-related protein LC3 B) (Microtubule-associated proteins 1A/1B light chain 3B). It may also react to mouse or rat LC3B, as predicted by immunogen homology.

同种型:

Rabbit IgG

免疫原:

A peptide corresponding to the N-terminus of human LC3B.

克隆号:

RM293

产品浓度:

N/A

保存温度:

+4°C

运输温度:

产品形式: