anti-LTbetaR (mouse), mAb (4H8 WH2) (preservative free)-单抗-深圳欣博盛生物科技有限公司

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anti-LTbetaR (mouse), mAb (4H8 WH2) (preservative free)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20B-0008PF-C100	规格：100 ug	目录价：￥3120
货号：AG-20B-0008PF-M001	规格：1 mg	目录价：￥18000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-LTbetaR (mouse), mAb (4H8 WH2) (preservative free)

别名:

Lymphotoxin-beta Receptor; Tumor Necrosis Factor Receptor 2 Related Protein; Tumor Necrosis Factor C Receptor; Tumor Necrosis Factor Receptor Superfamily Member 3; TNFRSF3

产品描述:

The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.

宿主来源:

Purified from concentrated hybridoma tissue culture supernatant.

实验应用:

FACS, FUNC (Blocking)

靶标/特异性:

Recognizes mouse LTbetaR.

同种型:

Rat IgG2a

免疫原:

Recombinant mouse LTbetaR (cysteine-rich region/aa 31-221).

克隆号:

4H8 WH2