anti-RIG-I, mAb (Alme-1) (Biotin)-单抗-深圳欣博盛生物科技有限公司

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anti-RIG-I, mAb (Alme-1) (Biotin)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20B-0009B-C100

规格：100 ug

目录价：￥5520

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-RIG-I, mAb (Alme-1) (Biotin)

别名:

RIG-1; Retinoic Acid-inducible Gene 1 Protein; DEAD-box Protein 58; Probable ATP-dependent RNA Helicase DDX58

产品描述:

RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-I recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.

宿主来源:

Purified from concentrated hybridoma tissue culture supernatant.

实验应用:

IHC, IP, WB

靶标/特异性:

Recognizes human and mouse RIG-I.

同种型:

Mouse IgG1

免疫原:

Recombinant human RIG-I (aa 201-713).

克隆号:

Alme-1