anti-MDA5 (mouse), pAb (AL180) (25 ug)-多抗-深圳欣博盛生物科技有限公司

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anti-MDA5 (mouse), pAb (AL180) (25 ug)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-25B-0001V-C100	规格：100 ug	目录价：￥4200
货号：AG-25B-0001V-TRIAL	规格：25 ug	目录价：￥1620

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-MDA5 (mouse), pAb (AL180) (25 ug)

别名:

Helicard; Melanoma Differentiation-associated Gene 5

产品描述:

RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. MDA5, upon interaction with intracellular dsRNA (produced during viral replication), triggers a transduction cascade involving MAVS/IPS1, which results in the activation of NF-kappaB, IRF3 and IRF7 and the induction of the expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). MDA5 is widely expressed at low levels. The expression is detected at higher levels in placenta, pancreas and spleen and barely in brain, testis and lung. Genetic variation in MDA5 is associated with diabetes mellitus insulin-dependent type 19 (IDDM19). A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy.

宿主来源:

Rabbit

实验应用:

IHC, WB

靶标/特异性:

Recognizes mouse MDA5.

免疫原:

Recombinant mouse MDA5 (aa 2-208).

产品浓度:

1mg /ml

保存温度:

+4°C