| 货号:REV-31-1381-00-R100 | 规格:100 ul | 目录价:¥5726 |
产品详情
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产品名称:
anti-MUC-1 (Mucin-1) (human), Rabbit Monoclonal (RM489)
别名:
MUC1; Cancer Antigen 15-3 (CA 15-3); CD227; Breast Carcinoma-associated Antigen DF3; Episialin; H23AG
产品描述:
MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. MUC1 is a transmembrane glycoprotein with a large mucin-like extracellular domain that matures through several intermediate forms generated by proteolysis, and sequential addition and processing of numerous O-linked glycans that are heavily sialylated. MUC1 is highly polymorphic and each allele encodes a product that contains a different number of repeats (between 30 and 90) leading to large differences in molecular weight of the protein. MUC1 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells, and is expressed abundantly in >90% breast carcinomas and metastases. Overexpression, aberrant intracellular localization, and changes in glycosylation of the MUC1 protein have been associated with carcinomas.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
This antibody reacts to human Muc-1 (Mucin-1).
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to the cytoplasmic domain of human Mucin-1.
克隆号:
RM489
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-Phospho-ULK1 (Ser757), Rabbit Monoclonal (RM488)
下一个:anti-TIA1 (human), Rabbit Monoclonal (RM490)
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