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折扣/货期| 货号：REV-31-1382-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-TIA1 (human), Rabbit Monoclonal (RM490)
别名:
T-cell-restricted Intracellular Antigen-1; Cytotoxic Granule Associated RNA-binding Protein TIA1
产品描述:
TIA1, also named as p40-TIA-1, is involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). It possesses nucleolytic activity against cytotoxic lymphocyte target cells. TIA1 may be involved in apoptosis. Similar to the ALS-related disease proteins TDP-43, hnRNPA1, and FUS, TIA1 is an RNA-binding protein containing a prionlike LCD and assembles into membrane-less organelles, including SGs. TIA1 mutations significantly increased the propensity of TIA1 protein to undergo phase transition. In live cells,TIA1 mutations delayed stress granule (SG) disassembly and promoted the accumulation of non-dynamic SGs that harbored TDP-43.
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
This antibody reacts to human TIA-1.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to the C-terminus of human TIA1.
克隆号:
RM490
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-MUC-1 (Mucin-1) (human), Rabbit Monoclonal (RM489)
下一个:anti-Trimethyl-Histone H3 (Lys36), Rabbit Monoclonal (RM491)
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