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折扣/货期| 货号：REV-31-1140-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-N-Cadherin (human), Rabbit Monoclonal (RM259)
别名:
CDH2; CD325
产品描述:
Cadherins are a superfamily of transmembrane glycoproteins that contain cadherin repeats of approximately 100 residues in their extracellular domain. Cadherins mediate calcium-dependent cell-cell adhesion and play critical roles in normal tissue development. The classic cadherin subfamily includes N-, P-, R-, B-, and E-cadherins, as well as about ten other members that are found in adherens junctions, a cellular structure near the apical surface of polarized epithelial cells. N-Cadherin (neuronal cadherin) is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. N-cadherin plays a role in neurons, in cardiac muscle and in cancer metastasis. While mutations in N-Cadherin have not thus far been associated with human disease, alterations in expression and integrity of N-cadherin protein has been observed in various forms of disease, including human dilated cardiomyopathy.
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
This antibody reacts to human N-cadherin. This antibody may also react to mouse or rat N-cadherin, as predicted by immunogen homology.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to Human N-Cadherin.
克隆号:
RM259
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-Synaptophysin (human), Rabbit Monoclonal (RM258)
下一个:anti-Acetyl-Histone H2B (Lys23), Rabbit Monoclonal (RM260)
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